Simple, easy and free ways to send large files online:

Gmail

It’s an email service, but it’s good. Gmail recently upped the maximum attachment size from 10 to 20 MB.
Registration: Required
Cost: Free
Max. file size: 20 MB

Drop Send

Ryan Carson’s app. Nice user interface to organize your files. Kind of like an online hard drive.
Registration: Required
Cost: Free (paid plans available)
Max. file size: 1 GB

Senduit

Squeaky clean Senduit is darn simple. You upload large files and Senduit stays out of your way.
Registration: Not required
Cost: Free
Max. file size: 100 MB

You Send It

A very capable little app with lots of paid options like secure downloads and return reciepts.
Registration: Not required
Cost: Free (paid plans available)
Max. file size: 100 MB

Mail Big File

So simple my grandma could do it. Really. Free sending of files to 1 recipient. Up to 100 MB.
Registration: Not required
Cost: Free (paid plans available)
Max. file size: 100 MB

Send Space

Upload via the web interface or using the desktop wizard application. Upload multiple file at once.
Registration: Not required
Cost: Free (paid plans available)
Max. file size: 300 MB

zUpload

Registration: Not required
Cost: Free
Max. file size: 500 MB

Media Max

Registration: Required
Cost: Free (paid plans available)
Max. file size: 10 MB

Mega Upload

Registration: Not required
Cost: Free (paid plans available)
Max. file size: 500 MB

Bit Road

Registration: Not required
Cost: Free
Max. file size: Unlimited

Media Fire

Registration: Not required
Cost: Free
Max. file size: 100 MB

Transfer Big Files

Registration: Not required
Cost: Free
Max. file size: 1 GB

Aruna Send

Registration: Not required
Cost: Free
Max. file size: 100 MB

BigFilez

Registration: Not required
Cost: Free (paid plans available)
Max. file size: 200 MB

Big Upload

Registration: Not required
Cost: Free (paid plans available)
Max. file size: 50 MB

Box Cloud

Registration: Required
Cost: Free (paid plans available)
Max. file size: Unlimited

Driveway

Registration: Not required
Cost: Free (paid plans available)
Max. file size: 500 MB

File Factory

Registration: Not required
Cost: Free (paid plans available)
Max. file size: 500 MB

Just Up It

Registration: Not required
Cost: Free
Max. file size: 170 MB

Leap File

Registration: Required
Cost: Paid plans
Max. file size: 2 GB

localhostr

Registration: Required
Cost: Free
Max. file size: 50 MB

Move Digital

Registration: Required
Cost: Paid plans
Max. file size: 1 GB

Panda File

Registration: Not required
Cost: Free
Max. file size: Unlimited